Inflammation · µmol/L

Homocysteine

Homocysteine is an amino acid formed during protein metabolism. To break it down, your body needs B vitamins (B12, folate, B6). If these are lacking, homocysteine accumulates.

Ranges we useRefsum et al. (Hordaland Homocysteine Study)
RatingRangeWhat it means
Goodbelow 10 µmol/LAt optimum — your blood vessels are protected.
Worth improving10 – 15 µmol/LSlightly elevated — often a deficiency of B6/B12/folate.
Talk to a doctor15 µmol/L and aboveElevated — check your B vitamins; seek advice.

This marker also has 5 age- or sex-specific range sets in the app — the table shows the general one.

Source: Refsum et al. (Hordaland Homocysteine Study) · The Hordaland Homocysteine Study · 2006 · open

Why it matters

An elevated level often points to a B-vitamin deficiency (folate, B12, B6).

If it’s low

Low homocysteine is favorable and no cause for concern.

If it’s high

Elevated homocysteine often means a deficiency of B12, folate or B6; it can also indicate poorer kidney function. The clinical benefit of lowering it alone is limited, but low B-vitamin levels are worth correcting.

What to do

Check and correct B12/folate/B6 (food or a supplement after consultation), limit alcohol. Homocysteine is more of an indicator than a standalone target.

Read together with

Vitamin B12 · Folate · eGFR

Part of the guide: Inflammation →

Articles about this marker

This content is for information only and is not a substitute for medical advice. Talk to your doctor about your results.

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