Fibrinogen
Fibrinogen is a blood-clotting protein (the fibrin mesh of a clot is formed from it). It is at the same time an inflammatory marker — the liver secretes more of it during inflammation.
| Rating | Range | What it means |
|---|---|---|
| Talk to a doctor | below 2 g/L | Low — interpret in context (liver/consumption); seek advice. |
| Good | 2 – 4 g/L | Within range. |
| Talk to a doctor | 4 g/L and above | Elevated — an inflammatory/thrombotic context. |
Why it matters
ISTH: elevated with inflammation/thrombotic risk; low with liver issues/consumption.
If it’s low
Low fibrinogen is less common; it can mean impaired production (severe liver disease) or increased consumption — important in bleeding.
If it’s high
Elevated fibrinogen indicates inflammation or increased clotting. It often accompanies infection, chronic inflammation, smoking or pregnancy.
What to do
Interpret it in the context of inflammation. To reduce chronic inflammation: quitting smoking, an anti-inflammatory lifestyle, a healthy weight. Low fibrinogen belongs to a doctor.
Read together with
hs-CRP · ESR · INR · aPTT
Part of the guide: Inflammation →
Articles about this marker
- High ESR (sedimentation rate): what it means, normal range and ESR vs CRPMarker explained
- How to lower inflammation (hs-CRP): an action planHow to improve
This content is for information only and is not a substitute for medical advice. Talk to your doctor about your results.
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